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MATHÄUS TSCHAIKOWSKY

PhD student

Früherkennung von Arthrose
00:00 / 10:19

Research

 

Osteoarthritis is a major burden for patients and health care systems and still the most common cause of disability. In cooperation with G.E.R.N. lab (Universitätsklinikum Freiburg) we study the nanomechanical and morphological changes in human articular cartilage (AC) at the early stages of disease. Using Atomic Force Microscopy (AFM) in combination with fluorescence microscopy we are gaining insights into the pathology of the tissue on a nanometer scale.

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About me

06/20: Doctoral scholarship from the German Academic Scholarship Foundation (Studienstiftung des deutschen Volkes)

07/19: Alumni award of the Faculty of Chemistry and Pharmacy, Albert-Ludwigs-Universität Freiburg

since 11/2018: PhD student in the Hugel/Balzer Lab

10/18: MSc Biochemistry and Biophysics (very good with honors), Albert-Ludwigs-Universität Freiburg       Topic: Nanomechanical properties of human osteoarthritic cartilage
AK Prof. Dr. Hugel and AG Prof. Dr. Bernd Rolauffs (G.E.R.N. lab)

10/16: BSc Chemistry, Albert-Ludwigs-Universität Freiburg and ETH Zürich

 

Awards

 

07/19: Poster award for “Towards a mechanistic understanding and detection of early-onset osteoarthritis” (Tag der Forschung, Freiburg)

Publications

 

-2021-

M. Tschaikowsky, T. Neumann, S. Brander, H. Haschke, B. Rolauffs, B.N. Balzer & T. Hugel
Hybrid fluorescence-AFM explores articular surface degeneration in early osteoarthritis across length scales

Acta Biomaterialia, 126, 315-325 (2021); https://doi.org/10.1016/j.actbio.2021.03.034

M. Tschaikowsky, M. Selig, S. Brander, B.N. Balzer, T. Hugel & B. Rolauffs
Proof-of-concept for the detection of early osteoarthritis pathology by clinically applicable endomicroscopy and quantitative AI-supported optical biopsy

Osteoarthritis and Cartilage, 29 (2), 269-279 (2021); https://doi.org/10.1016/j.joca.2020.10.003